{"id":6317,"date":"2024-05-21T14:46:45","date_gmt":"2024-05-21T12:46:45","guid":{"rendered":"https:\/\/lgr.upol.cz\/?page_id=6317"},"modified":"2025-01-09T13:15:59","modified_gmt":"2025-01-09T12:15:59","slug":"patenty","status":"publish","type":"page","link":"http:\/\/lgr.upol.cz\/en\/patenty\/","title":{"rendered":"Patents"},"content":{"rendered":"[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none”][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”80″][vc_column_text]Patents granted in 2024 \u2013 license possibilities<\/strong><\/p>\n

Gonzalez G,\u00a0Mik V, Bucharov\u00e1 N,\u00a0Gr\u00faz J, Ka\u0148ovsk\u00fd P, Strnad M, Zatloukal M. Heterocyclic nitrogen-containing purine derivatives, pharmaceutical preparations containing these derivatives and their use in neuroprotection<\/strong>.\u00a0EP 3924353<\/a>. 28.03.2024<\/p>\n

Urban M,\u00a0Gonzalez G, Hodo\u0148\u00a0 J, Strnad M. Terpenoidn\u00ed deriv\u00e1ty, farmaceutick\u00e9 p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty a jejich pou\u017eit\u00ed p\u0159i neuroprotekci<\/strong>.\u00a0PV 2020-651<\/a>. 11\/01\/2024<\/p>\n

Dolezal K, Plihalova L, Vylicilova H, Zatloukal M, Plihal O,\u00a0Voller J, Strnad M, Van Staden J, Baskaran P, Kumari A, Aremu AO. 6-Aryl-9-glycosylpurines and use thereof<\/strong>.\u00a0EP 15774847<\/a>\u00a003\/04\/2024<\/p>\n

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Patents granted in 2023 \u2013 license possibilities<\/strong><\/p>\n

Kvasnica M,\u00a0Gonzalez G<\/strong>, Gorova V, Strnad M. Sterolov\u00e9 deriv\u00e1ty, p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty a jejich pou\u017eit\u00ed<\/strong>.\u00a0CZ309819<\/a>. 27.09.2023<\/p>\n

Varvuolyte G, Malina L, Bieliauskas A, Hosikova B, Simerska H, Kolarova H, Kleiziene N,\u00a0 Strnad M, Arbaciauskiene E,\u00a0Krystof V<\/strong>, Sackus A, Zukauskaite A. Pyrazole-indole conjugates for photodynamic treatment of cancer and bacterial infections<\/strong>.\u00a0EP4107145<\/a>. 02\/08\/2023<\/p>\n

Posp\u00ed\u0161il J,\u00a0Gr\u00faz J<\/strong>, Strnad M, Janovsk\u00e1 L, Kol\u00e1\u0159 M,\u00a0R\u00e1rov\u00e1 L<\/strong>. Fenolick\u00e9 dihydrobenzofuranov\u00e9 deriv\u00e1ty, l\u00e9\u010debn\u00e9 a kosmetick\u00e9 p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty a jejich pou\u017eit\u00ed<\/strong>.\u00a0CZ 309633<\/a>. 20\/04\/2023<\/p>\n

B\u00edbov\u00e1 J,\u00a0<\/strong>Mik V<\/strong>, Zatloukal M, Pl\u00edhalov\u00e1 L,\u00a0Gr\u00faz J<\/strong>, Sp\u00edchal L, Dole\u017eal K, Strnad M. 9-(2-Oxacycloalkyl)-9H-purine-2,6-diamine derivatives and their use for the treatment of skin disorders<\/strong>.\u00a0US11643413<\/a>. 09\/05\/2023<\/p>\n

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Patents granted in 2022 \u2013 license possibilities<\/strong><\/p>\n

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B\u00edbov\u00e1 J, M\u00edk V, Zatloukal M, Pl\u00edhalov\u00e1 L, Gr\u00faz J, Sp\u00edchal L, Dole\u017eal K, Strnad M (2022)
\n9-(2-Oxacycloalkyl)-9H-purine-2,6-DIAmine derivatives and their use for the treatment of skin disorders<\/strong>, Palack\u00fd University Olomouc, European Patent No. EP3615535. Patent specification is available from this location<\/a>.<\/p>\n

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Klos Dardan; Pl\u00edhalov\u00e1 Lucie; Zatloukal Marek; Dole\u017eal Karel; Koprna Radoslav; Strnad Miroslav; Walla Jan; Balonov\u00e1 Jarmila (2022) Mesyl\u00e1tov\u00e9 soli heterocyklick\u00fdch cytokinin\u016f, p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty a jejich pou\u017eit\u00ed<\/strong>. 309368<\/a>. Patent specification is available from this location.<\/p>\n

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H\u00f6nig Martin; Pl\u00edhalov\u00e1 Lucie; Dole\u017eal Karel; Voller Ji\u0159\u00ed; Strnad Miroslav; Sp\u00edchal Luk\u00e1\u0161; Pl\u00edhal Ond\u0159ej; Vost\u00e1lov\u00e1 Jitka; Rajnochov\u00e1 Svobodov\u00e1 Alena; Ulrichov\u00e1 Jitka; Kadlecov\u00e1 Alena (2022) Adenine derivatives and use thereof<\/strong>. EP3341371<\/a>. Patent specification is available from this location. RIV\/61989592:15640\/22:73615496<\/p>\n

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Patents granted in 2020 \u2013 license possibilities<\/strong><\/p>\n

Havl\u00ed\u010dek L, \u0160turc A, \u0159ezn\u00ed\u010dkov\u00e1 E, Jorda R, Kry\u0161tof V, Strnad M (2020)\u00a0 5-Alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidiny pro l\u00e9\u010den\u00ed lymfom\u016f <\/strong>(En.: 5-Alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidines for the treatment of lymphomas<\/strong>), Univerzita Palack\u00e9ho v\u00a0Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., n\u00e1rodn\u00ed patent \u010d. 308484. Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

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Patents granted in 2019 \u2013 license possibilities<\/strong><\/p>\n

B\u00edbov\u00e1 J, Mik V, Zatloukal M, Pl\u00edhalov\u00e1 L, Gr\u00faz J, Sp\u00edchal L, Dole\u017eal K, Strnad M (2019) Deriv\u00e1ty 9-(2-oxacykloalkyl)-9H-purin-2,6-diaminu, p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty a jejich pou\u017eit\u00ed<\/strong>, Univerzita Palack\u00e9ho v Olomouci, n\u00e1rodn\u00ed patent \u010d. 307868. Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

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Havl\u00ed\u010dek L, \u0160turc A, Kry\u0161tof V, Jorda R, Posp\u00ed\u0161il T, Zahler S, Vollmar A, Strnad M (2019) 5-substituted 7-[4-(2-pyridyl)phenylmethylamino]-3-iso propylpyrazolo[4,3-D]pyrimidine derivatives, use thereof as medicaments and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v.\u00a0v.\u00a0i., European Patent No. EP3294741, Patent specification is available from this location<\/a>.<\/p>\n

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H\u00f6nig M, Pl\u00edhalov\u00e1 L, Dole\u017eal K, Voller J, Strnad M, Sp\u00edchal L, Vost\u00e1lov\u00e1 J, Rajnochov\u00e1 Svobodov\u00e1 A, Ulrichov\u00e1 J, Kadlecov\u00e1 A, Pl\u00edhal O (2019) Adeninov\u00e9 deriv\u00e1ty a jejich pou\u017eit\u00ed<\/strong>, Univerzita Palack\u00e9ho v Olomouci, n\u00e1rodn\u00ed patent \u010d. 307722. Patent specification is available ???.<\/p>\n

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Kry\u0161tof V, Vym\u011btalov\u00e1 L, Libor Havl\u00ed\u010dek, Anton\u00edn \u0160turc, Radek Jorda, Tom\u00e1\u0161 Posp\u00ed\u0161il, Miroslav Strnad (2019) 5-Substituovan\u00e9-7-[4- (substituovan\u00e9)benzyl]amino-3- isopropylpyrazolo[4,3-d]pyrimidiny, jejich pou\u017eit\u00ed jako antirevmatika, a farmaceutick\u00e9 p\u0159\u00edpravky<\/strong>,\u00a0 \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., n\u00e1rodn\u00ed patent \u010d. 308056. Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

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Moravec Tom\u00e1\u0161, Navr\u00e1til Old\u0159ich, \u010ce\u0159ovsk\u00e1 Noemi, Plchov\u00e1 Helena, Vacul\u00edk Petr, Okle\u0161\u0165kov\u00e1 Jana (2019) Expresn\u00ed syst\u00e9m a zp\u016fsob exprese protein\u016f v rostlin\u00e1ch<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., n\u00e1rodn\u00ed patent \u010d. 308137. Patent specification is available from Czech Patent and Utility Model Database from this location.<\/a><\/p>\n

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Nisler Jaroslav, Zatloukal Marek, Sp\u00edchal Luk\u00e1\u0161, Koprna Radoslav, Dole\u017eal Karel, Strnad Miroslav (2019) 1,2,3-thiadiazol-5yl-urea derivatives, use thereof for regulating plant senescence and preparations containing these derivatives<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., European Patent No. EP3191482. Patent specification is available from United States Patent and Trademark Office from this location<\/a>.<\/p>\n

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Zahajsk\u00e1 L, Nisler J, Kadlecov\u00e1 A, Zatloukal M, Gr\u00faz J, Voller J, Dolezal K, Strnad M (2019) 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., European Patent No. EP3233861. Patent specification is available from United States Patent and Trademark Office from this location.<\/a><\/p>\n

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Patents granted in 2018 \u2013 license possibilities<\/strong><\/p>\n

Dole\u017eal K, Pl\u00edhalov\u00e1 L, Vyl\u00ed\u010dilov\u00e1 H, Zatloukal M, Pl\u00edhal O, Voller J, Strnad M, Bryksov\u00e1 M, Vo\u0161\u0165alov\u00e1 J, Rajnochov\u00e1 Svobodov\u00e1 A, Ulrichov\u00e1 J, Sp\u00edchal L (2018) 6-aryl-9-glycosylpurines and use thereof<\/strong>, Univerzita Palack\u00e9ho v Olomouci, US patent No. 10100077. Patent specification is available from United States Patent and Trademark Office from this location.<\/a><\/p>\n

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Havl\u00ed\u010dek L, \u0160turc A, Kry\u0161tof V, Jorda R, Posp\u00ed\u0161il T, Zahler S, Vollmar A, Strnad M (2017) 5-substituted 7-[4-(2-pyridyl)phenylmethylamino]-3-iso propylpyrazolo[4,3-d]pyrimidine derivatives, use thereof as medicaments and pharmaceutical compositions<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v.v.i., European Patent No. EP3294741. Patent specification is available from this location<\/a>.<\/p>\n

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Zahajsk\u00e1 L, Nisler J, Kadlecov\u00e1 A, Zatloukal M, Gr\u00faz J, Voller J, Dolezal K, Strnad M (2018) 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., US patent No. 10093675. Patent specification is available from United States Patent and Trademark Office from this location.<\/a><\/p>\n

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Nisler J, Zatloukal M, Sp\u00edchal L, Koprna R, Dolezal K, Strnad M (2018) 1,2,3-thiadiazol-5yl-urea derivatives, use thereof for regulating plant senescence and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., US patent No. 9993002. Patent specification is available from United States Patent and Trademark Office from this location.<\/a><\/p>\n

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Nisler J, Zatloukal M, Sp\u00edchal L, Koprna R, Dolezal K, Strnad M (2018) 1,2,3-thidiazol-5yl-urea derivatives, use thereof for regulationg plant senescence and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., South Aftican Patent No. ZA 2017\/01338. Patent specification is available from Companies and Intellectual Property Commission from this location.<\/a><\/p>\n

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Nisler J, Zatloukal M, Sp\u00edchal L, Koprna R, Dolezal K, Strnad M (2018) 1,2,3-thiadiazol-5yl-urea derivatives, use thereof for regulating plant senescence and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., European Patent No. EP3191482. Patent specification is available from European Patent Office from this location<\/a>.<\/p>\n

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Havl\u00ed\u010dek L, \u0160turc A, Kry\u0161tof V, Jorda R, Posp\u00ed\u0161il T, Zahler \u0160, Vollmar A, Strnad M (2018) 5-substituted 7-(4-(2-pyridyl)phenylmethylamino)-3-isopropylpyrazolo-4,3-d-pyrimidines<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., US patent No. 9957273. Patent specification is available from United States Patent and Trademark Office from this location.<\/a><\/p>\n

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Patents granted in 2017 \u2013 license possibilities<\/strong><\/p>\n

Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Mikulits W, Strnad M (2017) N2-substituted-N6-(aryl-pyridine-3-ylmethyl)-9-cyclopentyl-9H-purine-2,6-diamine derivatives as tumor suppressor p53 activator for inhibiting angiogenesis and for treating cancer<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Biopatterns s.r.o., European Patent No. EP2953951. Patent specification is available from this location<\/a>.<\/p>\n

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Zatloukal M, Kry\u0161tof V, Havl\u00ed\u010dek L, Popa I, Dole\u017eal K, Strnad M, Jorda R (2017) Substituted 6-(2-hydroxybenzylamino)purine derivatives, their use as medicaments and compositions containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Biopatterns s.r.o., European Patent No. EP2438068. Patent specification is available from this location<\/a>.<\/p>\n

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Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Mikulits W, Strnad M (2017) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioPatterns s.r.o., Canadian Patent No. 2900292. Patent specification is available from this location<\/a>.<\/p>\n

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Patents granted in 2016 \u2013 license possibilities<\/strong><\/p>\n

Mik V\u00e1clav; Sz\u00fc\u010dov\u00e1 Lucie; Dole\u017eal Karel; Sp\u00edchal Luk\u00e1\u0161; Galuszka Petr; Strnad Miroslav; Gr\u00faz Ji\u0159\u00ed (2016) Use of 6-substituted 9-halogenalkyl purines for regulation of growth and development of whole plants, plant cells and plant organs; novel 6-substituted 9-halogenalkyl purines<\/strong>, Univerzita Palack\u00e9ho v Olomouci, European Patent No. EP2613631. Patent specification is available from this location<\/a>.<\/p>\n

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Nisler J, Zatloukal M, Koprna R, Sp\u00edchal L, Strnad M, Dole\u017eal K (2016) Pou\u017eit\u00ed N-furfuryl-N\u00b4-1,2,3-thiadiazol-5-yl mo\u010doviny pro inhibici senescence, stresu a oxidativn\u00edho po\u0161kozen\u00ed<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v.v.i., n\u00e1rodn\u00ed patent \u010d. 306009. Patent specification is available from this location<\/a>.<\/p>\n

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Nisler J, Zatloukal M, Koprna R, Sp\u00edchal L, Strnad M, Dole\u017eal K (2016) Deriv\u00e1ty 1,2,3-thiadiazol-5-yl mo\u010doviny, jejich pou\u017eit\u00ed pro regulaci senescence rostlin a p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto deriv\u00e1ty<\/strong>, n\u00e1rodn\u00ed patent \u010d. 305649. Patent specification is available from this location<\/a>.<\/p>\n

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Guck\u00fd T, Jorda R, Kry\u0161tof V, Mikulits W, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Strnad M, Zatloukal M (2016) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioPatterns s.r.o. Australian Patent No. AU2014214355. Patent specification is available from this location<\/a>.<\/p>\n

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Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Strnad M, Mikulits W (2016) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, New Realand Patent No. NZ 710291. Patent specification is available from this location<\/a>.<\/p>\n

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Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Mikulits W, Strnad M (2016) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioPatterns s.r.o., South African Patent No. ZA 2015\/05318. Patent specification is available from this location.<\/p>\n

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Zahajsk\u00e1 Lenka; Hanu\u0161 Jan; Sp\u00edchal Luk\u00e1\u0161; Voller Ji\u0159\u00ed; Strnad Miroslav; Zatloukal Marek (2016) 6,8-disubstituted purine compositions and their pharmaceutical and cosmetic use<\/strong>, EP2755977. Patent specification is available from this location<\/a>.<\/p>\n

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Strnad M, Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Mikulits W (2016) 2-substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioPatterns s.r.o., Singapore Patent No. SG 11201505640V. Patent specification is available ???.<\/p>\n

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Szu\u010dov\u00e1 (Pl\u00edhalov\u00e1) L, Zatloukal M, Sp\u00edchal L, Frohlich L, Dole\u017eal K, Strnad M, Massino FJ (2016) Derives de purine 6,9-disubstitutes et leur utilisation pour le traitement de la peau\/6,9-disubstituted purine derivatives and their use for treating skin<\/strong>, Canadian Patent No. CA2657516. Patent specification is available from this location<\/a>.<\/p>\n

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Szu\u010dov\u00e1 (Pl\u00edhalov\u00e1) L, Zatloukal M, Sp\u00edchal L, Frohlich L, Dole\u017eal K, Strnad M, Massino FJ (2016) 6,9-disubstituted purine derivatives for cosmetic use<\/strong>, European Patent No. EP2043630. Patent specification is available from this location<\/a>.<\/p>\n

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Voller J, Zahajsk\u00e1 L, Pl\u00edhalov\u00e1 L, Kom\u00e1rkov\u00e1 J, Burget D, Kry\u0161tof V, Zatloukal M, Dole\u017eal K, Strnad M, Rosel D, Br\u00e1bek J, Pataki AC\u00a0 (2016)2,6-disubstituovan\u00e9 puriny pro pou\u017eit\u00ed jako l\u00e9\u010diva, a farmaceutick\u00e9 p\u0159\u00edpravky<\/strong>, n\u00e1rodn\u00ed patent \u010d. 306434. Patent specification is available from this location<\/a>.<\/p>\n

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Patents granted in 2015 \u2013 license possibilities<\/strong><\/p>\n

Havl\u00ed\u010dek L, Kry\u0161tof V, Zatloukal M, Dole\u017eal K, Strnad M, Vojt\u011b\u0161ek B (2015) Substituted 6-(2-aminobenzylamino)purine derivatives, their use as medicaments and preparations containing these compounds<\/strong>, \u00a0<\/strong>Univerzita Palack\u00e9ho v Olomouci, US9023857. Patent specification is available from this location<\/a>. Licenced by Psortech, USA<\/p>\n

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Mik V, Sz\u00fc\u010dov\u00e1 L, Dole\u017eal K, Sp\u00edchal L, Galuszka P, Strnad M, Gr\u00faz J (2015) Use of 6-substituted 9-halogenalkyl purines for regulation of growth and development of whole plants, plant cells and plant organs; novel 6-substituted 9-halogenalkyl purines<\/strong>, Palack\u00fd University Olomouc, US patent No. 9220269. Patent specification is available at United States Patent and Trademark Office from this location<\/a>.<\/a><\/p>\n

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Zatloukal M, Dole\u017eal K, Voller J, Sp\u00edchal L, Strnad M (2015) Substitution derivatives of N.sup.6 -benzyladenosine-5\u2032-monophosphate, methods of preparation thereof, use thereof as medicaments, and therapeutic preparations containing these compounds<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioApex s.r.o., US 9073961. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Morzycki JW, Wojtkielewicz A, Okle\u0161\u0165kov\u00e1 J, Hoffmannov\u00e1 L, Strnad M (2015) Novel saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Uniwersytet W Bialymstoku, Univerzita Palack\u00e9ho v Olomouci a BioApex s.r.o., CA 2751263. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Sz\u00fc\u010dov\u00e1 (Pl\u00edhalov\u00e1) L, Zatloukal M, Sp\u00edchal L, Fr\u00f6lich L, Dole\u017eal K, Strnad M, Massino F (2015) 6,9-disubstituted purine derivatives and their use for treating skin<\/strong>, \u00daEB AV \u010cR (IEB ASCR), KR101478727. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Patents granted in 2014 \u2013 license possibilities<\/strong><\/p>\n

Guck\u00fd T, Jorda R, Zatloukal M, Kry\u0161tof V, R\u00e1rov\u00e1 L, \u0158ezn\u00ed\u010dkov\u00e1 E, Mikulits W, Strnad M (2014) 2-Substituted-6-biarylmethylamino-9-cyclopentyl-9H-purine derivatives, use thereof as medicaments, and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci, Biopatterns s.r.o., PCT\/CZ2014\/000014, WO2014121764 (A2). Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Havl\u00ed\u010dek L, Kry\u0161tof\u00a0 V, Zatloukal M, Dole\u017eal K, Strnad M, Vojt\u011b\u0161ek B (2014) Substituted 6-(2-aminobenzylamino)purine derivatives, their use as medicaments and preparations containing these compounds<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioApex s.r.o., European patent No. EP2391626. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Okle\u0161\u0165kov\u00e1 J, Hoffmanov\u00e1 L, Strnad M, Morzycki JW, Wojtkieliwicz A (2014) Novel saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Univerzita Palack\u00e9ho v Olomouci, Uniwersytet w Bialymstoku and BioApex s.r.o., European patent No. EP2393826. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Sz\u00fc\u010dov\u00e1 L, Kry\u0161tof V, Zatloukal M, Dole\u017eal K, Strnad M, Sp\u00edchal L (2014) Substituted 6-(benzylamino) purine riboside derivatives, use thereof and compositions containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Biopatterns s.r.o., European patent No. EP2430036. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Zatloukal M, Dole\u017eal K, Voller J, Sp\u00edchal L, Strnad M (2014) Substitution derivatives of N6-benzyladenosine-5-monophosphate, methods of preparation thereof, use thereof as medicaments, and therapeutic preparation containing these compounds<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioApex, s.r.o., patent No. EP2563801. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Sp\u00edchal L, Popa I, Voller J, Dole\u017eal K, Strnad M, Werner T, Schm\u00fclling T (2014) Substituted 6-(alkylbenzylamino)purine derivatives for use as cytokinin receptor antagonists and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Freie Universit\u00e4t Berlin, European patent No. EP2203451. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Okle\u0161\u0165kov\u00e1 J, Hoffmanov\u00e1 L, Strnad M, Morzycki JW, Wojtkieliwicz A (2014) Novel saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Palack\u00fd University Olomouc, Uniwersytet w Bialymstoku and BioApex s.r.o. Australian patent No. AU2010210218. Patent is registered at Australian Patent Office, download here<\/a>.<\/p>\n

 <\/p>\n

Strnad M, Dole\u017eal K, Zatloukal M, Gemrotov\u00e1 M, Galuszka P, Fr\u00e9bortov\u00e1 J, Sp\u00edchal L, Werner T, Schm\u00fclling T (2014) Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase\/dehydrogenase and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Freie Universit\u00e4t Berlin, Australian patent No. AU2008271800. Patent is registered at Australian Patent Office, download here<\/a>.<\/p>\n

 <\/p>\n

Szucova L, Zatloukal M, Spichal L, Voller J, Dolezal K, Strnad M, Massino FJ (2014) 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., European patent No. EP2245031. Patent specification is available from this location. <\/a><\/p>\n

 <\/p>\n

Dolezal K, Zatloukal M, Strnad M, Voller J, Szucova L, Spichal L, Massino FJ (2014) 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., Australian patent No. AU2008345103. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Hana Posp\u00ed\u0161ilov\u00e1, Petr Galuszka, Ivo Fr\u00e9bort (2014) Zp\u016fsob p\u0159\u00edpravy je\u010dmene se zv\u00fd\u0161enou odolnost\u00ed v\u016f\u010di suchu<\/strong>. Univerzita Palack\u00e9ho v Olomouci, National patent No. 304935. (Process for preparing barley with increased resistance to dry season) <\/em><\/strong>Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Patents granted in 2013 \u2013 license possibilities<\/strong><\/p>\n

Morzycki JW, Wojtkielewicz A, Okle\u0161\u0165kov\u00e1 J, Hoffmanov\u00e1 L, Strnad M (2013) Novel saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Palack\u00fd University Olomouc, Uniwersytet w Bialymstoku a BioApex s.r.o., New Zealand patent No. 594217. Patent specification is available from Intellectual Property Office of New Zealand from this location<\/a>.<\/p>\n

 <\/p>\n

Zatloukal M, Kry\u0161tof\u00a0 V, Havl\u00ed\u010dek L, Popa I, Dole\u017eal K, Strnad M, Jorda R (2013) Substituted 6-(2-hydroxybenzylamino)purine derivatives, their use as medicaments and compositions containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Biopatterns, s.r.o., US patent No. 8492391Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Morzycki JW, Wojtkielewicz A, Okle\u0161\u0165kov\u00e1 J, Hoffmanov\u00e1 L, Strnad M (2013) Saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Palack\u00fd University Olomouc, BioApex s.r.o. and Uniwersytet w Bialymstoku, US patent No. 8552161 Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Sp\u00edchal L, Gemrotov\u00e1 M, Zatloukal M, Fr\u00e9bortov\u00e1 J, Galuszka P, Dole\u017eal K, Werner T, Schm\u00fclling T (2013) Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase\/dehydrogenase and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Freie Universit\u00e4t Berlin, European patent No. EP2173173. Patent specification is available from this location<\/a>.<\/p>\n

 <\/p>\n

Zatloukal M, Voller J, Strnad M, Dole\u017eal K, Sp\u00edchal L (2013) Substitution derivatives of N6-benzyladenosine-5\u00b4-monophosphate, methods of their preparation, their use for preparation of medicament and therapeutic composition containing thereof<\/strong>, Univerzita Palack\u00e9ho v Olomouciand BioApex, South Africa patent No. ZA 2012\/07173 Patent specification is available from Companies and Intellectual Property Commission from this location<\/a>.<\/p>\n

 <\/p>\n

Petr Cankar, Iveta Frysova, Vladimir Krystof, Rene Lenobel, Jan Slouka, Miroslav Strnad, Peter Martin Fischer (GB) (2013) 4-arylazo-3,5-diamino-pyrazole compounds and use thereof<\/strong>, US patent No. 8357673. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Daniela Moravcov\u00e1, Libor Havl\u00ed\u010dek, Vladim\u00edr Kry\u0161tof, Rene Lenobel, Miroslav Strnad (2013) Novel pyrazolo-[4,3-D]pyrimidines, processes for their preparation and methods for therapy<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., Indidan patent No. 256069. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Popa, Jan Holub, Ren\u00e9 Lenobel, Stefaan Werbrouck (BE), Karel Dolezal, Miroslav Strnad, Marek Zatloukal, Frank J. Massino (2013) Heterocyclic compounds based on N6-substituted adenine, methods of their preparation, their use fur preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compouds<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., US patent No. 8552013. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Szucova Lucie [CZ]; Zatloukal Marek [CZ]; Spichal Lukas [CZ]; Frolich Ludek [CZ]; Dolezal Karel [CZ]; Strnad Miroslav [CZ]; Massino Frank J [US] (2013) 6,9-disubstituted purine derivatives and their use for treating skin<\/strong>, \u00dastav experiment\u00e1ln\u00ed botaniky AV \u010cR, v. v. i., Japan patent No. JP 5309023. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Lucie Szucova, Marek Zatloukal, Lukas Spichal, Jiri Voller, Karel Dolezal, Miroslav Strnad, Frank J. Massino (2013) 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions<\/strong>, US patent No. 8552013. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Patents granted in 2012 \u2013 license possibilities<\/strong><\/p>\n

Mik V, Sz\u00fc\u010dov\u00e1 L, Dole\u017eal K, Sp\u00edchal L, Galuszka P, Strnad M (2012) Pou\u017eit\u00ed 6-substituovan\u00fdch 9-halogenalkyl purin\u016f pro regulaci r\u016fstu a v\u00fdvoje rostlin, rostlinn\u00fdch org\u00e1n\u016f a bun\u011bk, nov\u00e9 6-substituovan\u00e9 9-halogenalkyl puriny<\/strong>, Univerzita Palack\u00e9ho v Olomouci, national patent No. 303054. (Use of 6-substituted 9-haloalkyl purines for regulating growth and development of plants, vegetable organs and cells, and novel 6-substituted 9-haloalkyl purines) <\/em><\/strong>Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

 <\/p>\n

Sp\u00edchal L, Gemrotov\u00e1 M, Zatloukal M, Fr\u00e9bortov\u00e1 J, Galuszka P, Werner T, Schm\u00fclling T, Dole\u017eal K, Strnad M (2012) Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase\/dehydrogenase and preparations containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci a Freie Universit\u00e4t Berlin, US patent No. 8222260. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Morzycki JW, Wojtkielewicz A, Okle\u0161\u0165kov\u00e1 J, Hoffmanov\u00e1 L, Strnad M (2012) Novel saponin compounds, methods of preparation thereof, use thereof and pharmaceutical compositions<\/strong>, Palack\u00fd University Olomouc, Uniwersytet w Bialymstoku and BioApex s.r.o., South Africa patent No. ZA 2011\/05443. Patent specification is available from Companies and Intellectual Property Commission from this location<\/a>.<\/p>\n

 <\/p>\n

Zatloukal M, Dole\u017eal K, Voller J, Sp\u00edchal L, Strnad M (2012) Substitu\u010dn\u00ed deriv\u00e1ty N6-benzyladenosin-5\u00b4-monofosf\u00e1tu, zp\u016fsoby jejich p\u0159\u00edpravy, tyto deriv\u00e1ty pro pou\u017eit\u00ed jako l\u00e9\u010diva a terapeutick\u00fd p\u0159\u00edpravek je obsahuj\u00edc\u00ed<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioApex s.r.o., national patent No. 303327. (Substitution derivatives of N6-benzyladenosine-5\u00b4-monophosphate, methods of their preparation, their use for preparation of medicament and therapeutic composition containing thereof) <\/em><\/strong>Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

 <\/p>\n

Kohout L, Chodounsk\u00e1 H, Hnili\u010dkov\u00e1 J, Kasal A, \u010cern\u00fd I, Kol\u00e1\u0159 Z, Strnad M, Okle\u0161\u0165kov\u00e1 J, Steigerov\u00e1 J, Hoffmanov\u00e1 L (2012) Pou\u017eit\u00ed cholestanov\u00fdch deriv\u00e1t\u016f k v\u00fdrob\u011b l\u00e9\u010diva pro l\u00e9\u010dbu n\u00e1dorov\u00e9ho bujen\u00ed a s n\u00edm spojen\u00e9 angiogeneze<\/strong>, Univerzita Palack\u00e9ho v Olomouci a \u00dastav organick\u00e9 chemie a biochemie AV \u010cR, v.v.i., national patent No. 303171. (Use of cholestane derivatives for preparing a medicament intended for the treatment of tumor proliferation and angiogenesis associated therewith). <\/em><\/strong>Patent specification is available from Czech Patent and Utility Model Database from this location<\/a>.<\/p>\n

 <\/p>\n

Sz\u00fc\u010dov\u00e1 L, Zatloukal M, Dole\u017eal K, Kry\u0161tof\u00a0 V, Sp\u00edchal L, Strnad M (2012) Substituted 6-(2-hydroxybenzylamino) purine derivatives, their use as medicament and compositions containing these derivatives<\/strong>, Univerzita Palack\u00e9ho v Olomouci \u00a0and BioPatterns s.r.o., South Africa patent No. ZA 2011\/07883. Patent specification is available from Companies and Intellectual Property Commission from this location<\/a>.<\/p>\n

 <\/p>\n

Havl\u00ed\u010dek L, Kry\u0161tof V, Zatloukal M, Dole\u017eal K, Strnad M, Vojt\u011b\u0161ek B (2012) Substituted 6-(2-aminobenzylamino)purine derivatives, their use as medicaments and preparations containing these compounds<\/strong>, Univerzita Palack\u00e9ho v Olomouci a BioApex s.r.o., South Africa patent No. ZA 2011\/04945. Patent specification is available from Companies and Intellectual Property Commission from this location<\/a>.<\/p>\n

 <\/p>\n

Moravcov\u00e1 Daniela, Havlicek Libor, Krystof Vladimir, Lenobel Rene, Binarova Pavla, Mlejnek Petr, Vojtesek Borek, Uldrijan Stjepan, Schmuelling Thomas, Strnad Miroslav (2012) Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use<\/strong>, Canadian patent No. CA 2524344. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Lucie Sz\u00fc\u010dov\u00e1, Zatloukal Marek, Sp\u00edchal Luk\u00e1\u0161, Frohlich Lud\u011bk, Dole\u017eal Karel, Strnad Miroslav (2012) 6,9-disibstituted purine derivatives and their use for treating skin<\/strong>, Australian patent No. AU 2007272576. Patent specification is available from this location.<\/a><\/p>\n

 <\/p>\n

Patent applications in 2011 \u2013 license possibilities<\/strong><\/p>\n

Mik V, Sz\u00fc\u010dov\u00e1 L, Dole\u017eal K, Sp\u00edchal L, Galuszka P, Strnad M, Gruz J (2011) Use of 6-substituted 9-halogenalkyl purines for regulation of growth and development of whole plants, plant cells and organs, novel 6-substituted 9-halogenalkyl purines<\/strong>, Univerzita Palack\u00e9ho v Olomouci, application No. PCT\/CZ2011\/000086<\/p>\n

 <\/p>\n

Galuszka P, Sz\u00fc\u010dov\u00e1 L, Sp\u00edchal L, Dole\u017eal K, Fr\u00e9bort I, Strnad M (2011) Pou\u017eit\u00ed 6,9-disubstituovan\u00fdch deriv\u00e1t\u016f N6-substituovan\u00fdch adenin\u016f v zem\u011bd\u011blstv\u00ed a p\u0159\u00edpravky obsahuj\u00edc\u00ed tyto slou\u010deniny<\/strong>, Univerzita Palack\u00e9ho v Olomouci, application No. PV2011-845 (Use of 6,9-disubstituted derivatives of N6-substituted adenines in agriculture and products containing these compounds<\/em>)<\/strong>[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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